The unit is specially designed, researched and developed for the purification of targeted compound in pharmaceutical industry. The preparative liquid chromatographic column has super high sample loading capacity, which has provided reliable guarantee for enhanc-ing the preparative quantity of purification products with lower cost.
It is widely used for extraction and refining of effective components in waste water treatment, protein, enzyme, monosaccharide, amylose and plant. The characteristics of chromatography separation are as follows: the operation condition is moderate (normal temperature, and normal pressure generally); the mixture can obtain multiple pure components at one time; precise separation is available so as to obtain products of high purity. Combining modern computer automatic control technology and technical parameter online detection technology, the unit has upgraded and reformed the traditional manual chromatography equipment to enhance the reliability and repetition. The equipment is easy for magnifying the chromatography technology to solve the problem of industrialized production.
The chromatographic separation technology mostly applied in the traditional Chinese medicine separation and purification can be mainly divided into absorption chromatography and ion exchange chromatography. The absorption chromatography includes reversed-phase chromatography (C18 filler) and normal phase silica gel chromatography. The ion exchange chromatography is mainly used for separation and purification of compound with electric charge. Currently, the chromatographic separation technology has played more and more functions in the refining of effective components of traditional Chinese medicine such as flavone, alkaloid, glycoside, organic acid and amylose etc.
Application of separation and purification of natural products
Development of small-scale test technology, magnifying research of pilotscale test technology, preparation of phytochemical standard products and contrasting products. Widely suitable for separating phenol, aldehyde, alkaloid, amino acid, steroid, terpene, flavone, quinine, organic acid, glycoside, glucide, nucleotide etc. pure products, such as: paclitaxel, tea polyphenol, ginkgo flavone, bamboo leave flavone and vitamin E etc.
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